Apo to genome tis Salmonella typhy CT18 vrite ola ta gonidia
pou kodikopoioun gia transposase tou IS200 (xrisimopoiwntas to Artemis).

("Is" stands for "Insertion Sequence")

Ftiaxte to multiple sequence alignment gia tis parapanw DNA akolou8ies

ftiaxte (build) to hmm gia tin parapanw oikogeneia akolou8iwn

trexte (search) to hmm pou ftiaxate sto genome tis Salmonella typhi CT18

metatrepste to output me ta predictions se .tab file pou mporei na
diavasei to Artemis kratontas tin pliroforia sxetikis 8esis twn provlepsewn mesa
sto gonidiwma kai to antistoixo hmm score.

metatrepste episis to score se xrwmatiki klimata leukou-kokkinou gia mikra kai megala antistoixa scores.

fortwste to tab file stin Artemis kai epi8ewriste ta apotelesmata.

yparxei overlap me to uparxon annotation gia transposases IS200?

ka8oriste me dunamiko tropo to optimal score threshold panw apo to opoio ta predictions einai statistika simantika.

meta tin efarmogi tou score threshold (mesa apo tin Artemis mporeite na emfanisete/ejafanisete predictions 
me score xamilotero tou cutoff tis epilogis sas) how many statistically significant predictions vriskete to
genome tis Salmonella typhy CT18?

epanalavate to search me to hmm pou ftiajate gia tin CT18 sto genome tis Salmonella typhy TY2,
fortwste to neo .tab file stin Ty2 kai sugkrinate ta apotelesmata me auta tis CT18.

optikopoiiste tis omoiotites kai diafores mesw tou Artemis Comparison Tool (ACT) fwrtwnontas ta duo
genomes (CT18 & TY2).

kataskeuaste fulogenetiko dendro xrisomopoiwntas oles tis (DNA) akolou8ies gia transposase IS200
pou vrikate se CT18 kai TY2. to fulogenetiko dendro pou ftiajate diaxwrizei fulogenetika ta IS200
tis CT18 apo auta tis TY2? Ean oxi proteinete pi8anous logous.